Drugs that can weaken erections in men

Adeyemi Maxwell

MAINTAINING a healthy and strong erection is important for men to engage in satisfying sexual activity. However, certain drugs, when taken regularly, can have a negative impact on erectile function. They generally affect the man’s hormones, nerves, or blood circulation, resulting in erectile dysfunction or they increase the risk of erectile dysfunction. It is crucial to be aware of the potential side effects of these medications and to discuss any concerns with a healthcare professional.

1. Antidepressants

A commonly prescribed class of medications, antidepressants can have adverse effects on sexual function, including the ability to achieve and maintain an erection. Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), which are commonly used to treat depression and anxiety, can interfere with the normal functioning of neurotransmitters in the brain. The disruption of serotonin and norepinephrine levels can lead to a decrease in sexual desire and difficulties in achieving or sustaining an erection.

2. Antihypertensive medications

High blood pressure is a prevalent condition, and many individuals rely on antihypertensive medications to manage it. Generally living with hypertension and treating the condition can be a case of “between a rock and a hard place."

If the high blood pressure is not treated, it may lead to erectile dysfunction as it may damage the blood vessels to the penis. However, treating the condition may also lead to erectile dysfunction.

Certain antihypertensive drugs, such as beta-blockers and diuretics, have been associated with erectile dysfunction. Beta-blockers work by blocking the action of adrenaline in the body, which can lead to a decrease in penile blood flow. Diuretics, on the other hand, can cause dehydration and electrolyte imbalances, which may impact erectile function.

It is important to note that not all antihypertensive medications have the same effect, and alternative medications that do not cause erectile dysfunction may be available for individuals experiencing these side effects.

3. Antipsychotic medications

Antipsychotic medications, commonly prescribed for various mental health conditions, have been shown to affect sexual function, including erectile function. These medications, such as risperidone and olanzapine, can block dopamine receptors in the brain.

Dopamine is an important neurotransmitter involved in sexual arousal and pleasure. By interfering with dopamine levels, antipsychotic medications can lead to sexual side effects, including difficulties in achieving and maintaining an erection.

4. Hormonal medications

Some hormonal medications, such as certain types of testosterone replacement therapy (TRT), can impact erectile function when used long-term. While testosterone replacement therapy can be beneficial for individuals with low testosterone levels, it is essential to monitor and adjust hormone levels carefully.

High levels of testosterone can lead to a decrease in the production of luteinising hormone (LH) and follicle-stimulating hormone (FSH), which are involved in the natural production of testosterone by the testes. As a result, long-term use of testosterone replacement therapy can potentially disrupt the normal hormonal balance, leading to difficulties with erections.

5. Antihistamines

Antihistamines are commonly used to treat allergies and relieve symptoms such as itching, sneezing and runny nose. However, some antihistamines, such as diphenhydramine and cetirizine, can have a drying effect on the body. This can include reducing mucous membrane secretions and decreasing penile blood flow, potentially leading to difficulties in achieving or maintaining an erection.

It is important to note that not all antihistamines have this effect, and alternative options may be available.

6. Opioids

Opioid medications, such as codeine, oxycodone and morphine, are potent pain relievers. However, their use can have significant impacts on sexual function. Opioids can lead to a decrease in testosterone levels, disrupt hormonal balance, and affect neurotransmitter activity in the brain. These factors can contribute to erectile dysfunction and decreased sexual desire.

Additionally, opioids can have sedative effects, which can further exacerbate sexual difficulties. It is essential to carefully consider the risks and benefits of opioid medications and to explore alternative pain-management strategies if possible.

7. Muscle relaxants

Muscle relaxants are often prescribed to relieve muscle spasms and promote relaxation. While they are effective in reducing muscle tension, some muscle relaxants may have adverse effects on erectile function. These medications can interfere with nerve transmission and disrupt normal muscle co-ordination, potentially leading to difficulties in achieving and maintaining an erection.

8. Chemotherapy drugs

Chemotherapy drugs, used in the treatment of various types of cancer, can have a wide range of side effects. Among these side effects, erectile dysfunction is not uncommon. Chemotherapy drugs can impact the cardiovascular system, hormonal balance, and neurological function, all of which are crucial for healthy erectile function.

Discussing the potential impact on sexual health and exploring supportive strategies with a healthcare team is essential for individuals undergoing chemotherapy.

9. Epilepsy drugs

Medications used to treat epilepsy or seizure disorders such as phenytoin (Dilantin) can cause or increase the risk of erectile dysfunction.

10. Anti-ulcer medications

Certain classes of drugs known as the histamine receptor antagonists, such as cimetidine, famotidine and ranitidine, are also known to cause erectile problems.

11. Parkinson medications

Drugs used to treat neurological disease like Parkinson’s disease also have the potential to interfere with sexual functions in men. Levodopa (Sinemet) and Cogentin are common examples of these drugs.

Other substances and drugs that can cause or lead to erectile dysfunction include recreational and frequently abused drugs such alcohol, cocaine, marijuana, nicotine and methadone.

If you experience erectile dysfunction while on a particular medication to treat an ailment, do not stop taking the drug without first consulting with your doctor. If the problem persists, your doctor may be able to prescribe a different medication.

Contact Dr Maxwell on 3631807 or 7575411